Optigen is the unique official provider of this DNA test in the US.
This test has been developped by a European Lab called ANTAGENE
How Shall I produce Healthy AMSTAFF puppies?
Make sure you're breeding healthy dogs by selecting your brood bitch and stud dog.
Select your dogs by knowing there genetic status vs Cerebellar ataxia.
A DNA test is required to know it (NCL-A test)
3 genetic status are possible:
"Normal Homozygous" (clear) :
Your dog isn't carrying the mutation and will not transmit it to its progeny.
Advice: You can mate this dog with a "clear" or "carrier" dog.
Your dog will not develop the disease but has a 50% chance to transmit the mutation to its progeny » . Your dog can produce « affected » puppies (Mutated Homozygous) if mated with another dog « carrier»
Advice: Mate your dog with an "clear" (normal homozygous) dog
"Mutated Homozygous" (affected):
Your dog is affected and will develop the signs of the disease. He has a 100% chance to transmit it to its progeny
More info about the disease:
Cerebellar ataxia is an hereditary disease.
7% of the dogs of the breed is developping signs of the disease.
Age of onset: 3 to 5 years old
The symptoms are:
- "Wobbly" gait
- Loss of balance
At the final stage, the dog is unable to move and euthanasia is generally practiced.
Your dog can be carrying the mutation (30% of AMSTAFF population) without developing the disease, but can transmit it to its puppies.
Stop getting AMSTAFF affected by cerebellar ataxia !
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